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A review on solid dispersion and latest approaches used to improve solubility of poorly water soluble drugs

Author : Ramanpreet Kaur and Sandeep Kumar

In the present day solubility of drugs in GIT fluids becomes necessary for the preparation of solid unit dosage forms of drugs. Otherwise if the drug has poor solubility then the drug does not show its effect properly in the body. So, solubility is a main aspect in the formulation of unit doses. Various methods like Lyophilization (Freeze drying process), Super critical fluid technology, Nanotechnology, Liquisolid compact technology, Self-emulsifying agents (SMEDDS) etc. are used to improve the solubility and dissolution rate of poorly water soluble drugs.


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