Biosynthesis of silver nanoparticles using Cordia macleodii (Griff.) Hook. F & Thomas and its antibacterial activity
Biogenic synthesis of silver nanoparticles is eco friendly and cost effective as compared to physical and chemical process. In the present investigation, an attempt was made for the synthesis of silver nanoparticles using stem extracts of Cordia macleodii (Griff.) Hook. F & Thomas. UV–Vis absorption spectroscopy, Fourier Transfer Infra Red (FTIR) and Scanning Electron Microscope (SEM) were used for the characterization of synthesized silver nanoparticles. Silver colloidal solution showed absorption maxima at 424 and 437.4 nm which indicated formation of silver nanoparticles. The synthesized nanoparticles showed significant antibacterial activity against nine different pathogenic bacterial strains such as Pseudomonas aeruginosa, Staphylococcus aureus, Citrobacter sp., E.coli, CONS (Coagulase negative Staphylococci), Acinetobacter sp., Enterobacter sp., Proteus vulgaris and Klebsiella sp. Maximum antibacterial activity was observed against Staphylococcus aureus (15.1 mm) followed by Citrobacter sp.(14.0 mm) and Klebsiella sp.(11.9mm). Efforts should be made for detail investigation on efficacy, longevity and toxicity of synthesised nanoparticles and its applications in pharmacological and clinical trials.
Full Text Attachment