Article

Cytotoxic, antioxidant and antimicrobial activities of Ipomoea carnea spp. fistulosa (Mart. ex Choisy) D. Austin

Author : Marwa Hasan, Souzan Ibrahim, Kamilia Abo El-Seoud, Mona El-Aasr

Cytotoxic, antioxidant and antimicrobial activities of Ipomoea carnea spp. fistulosa (Mart. ex Choisy) D. Austin were evaluated. The n-butanol fraction of the leaves showed the highest cytotoxic activity on MCF-7 and HpeG2 cell lines. The methanolic extract from the flowers showed the highest antioxidant activity (using DPPH radical scavenging test). Furthermore, the antimicrobial activity was carried out against Staphylococcus aureus, Escherichia coli, Candida albicans and Penicillium chrysogenum. The methanolic extract from the leaves and its n-butanol fraction showed higher indicative antibacterial activity. 2-C-methyl-D-erythritol and quercetin were isolated for the first time, in addition to β-sitosterol, umbelliferone, kaempferol-3-O-β-D-glucoside (astragalin) and swainsonine alkaloid.


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