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Determination of antioxidant activity of the selected extracts of Mathuka Neriifolia (Moon) H.J. Lam, isolation and characterization of phytoconstituents of the ethanol extract by column chromatography.

Author : Minu B. Pattasseril, Sivakumar T, Kuppuswami S

The present study involves the determination of antioxidant activity of the selected extracts of Mathuka Neriifolia (Moon) H.J. Lam, isolation and characterization of phytoconstituents of the ethanol extract by column chromatography.The antioxidant potential of plant stem extracts were investigated by hydroxyl radical scavenging activity, super oxide free radical scavenging activity, DPPH assay, nitric oxide radical scavenging activity, total antioxidant activity. Among the three extracts ethanol extract was having maximum antioxidentactivity. So the ethanol extract was subjected to column chromatography,by means of gradient elution technique.The fractions 260 300 and 301 344 ,gave two compounds A 1 and A 2.Later by spectral analysis they were found to be Quercetin and Luteolin 7 glucoside.


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