Effect on the biochemical and hematological parameters on Rasa Mezhugu in Freundís adjuvant-induced arthritis rats

Author : K. Nandhagopal and M. Kanniyakumari

Rheumatoid Arthritis (RA) is a chronic, destructive inflammatory poly-articular joint and systemic autoimmune disease. It typically results in warm, swollen, and painful joints, stiffness often worsen following rest. The goal of treatment is to reduce pain, decrease inflammation, and improve a person's overall functioning. In spite of tremendous development in the field of synthetic drugs during recent years, the side effects could not be avoided. Hence the current research focus is to develop less toxic drugs as early as feasible in the disease process. A 90 day old Wistar male rat was used for the research and was divided in to four groups treated with Saline, Palm Jaggary, Rasa Mezhugu and Indomethacin. Evaluation of anti-arthritic potency, by body weight, biochemical and hematological analysis were analyzed. Rasa Mezhugu treatment rats have significantly reduces the Arthritis effect induced by complete Freund's adjuvant (CFA)-induced arthritic rat.

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