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Evaluation of in vitro antidiabetic activity of red seaweed Portieria hornemannii (Lyngbye) (Silva) and Spyridia fusiformis (Wulfen)

Author : Murugesan S, Bhuvaneswari S and Sivamurugan V

In the present study in vitro antidiabetic activity of red seaweed Portieria hornemannii (Lyngbye) (Silva) and Spyridia fusiformis (Wulfen) were evaluated using α-amylase and α-glucosidase for inhibitory activity. The methanol extract of Spyridia fusiformis revealed at the concentration of 900 g/mL, α-amylase shows higher activity (84.72 g/g) than α-glucosidase (94.75 g/g). The IC50 values wer7e achieved high in S. fusiformis at 430 g/mL in α-amylase and 60 g/mL in α-glucosidase, nevertheless the IC50 value of α-amylase shows a twofold higher than the α-glucosidase. Thus, our results suggest that P.ornemannii and S. fusiformis could be used as a potent antidiabetic agent.


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