In-vivo Anti-inflammatory activity of Pyrus pashia Fruit

Author : Subhash Chandra, Sarla Saklani, Sarvesh Kumar

In the present study, we investigated the in vivo anti-inflammatory activity of the methanolic extract of Pyrus pashia fruits. The methanolic extract of Pyrus pashia fruits at 100 mg/kg body weight per day given orally as a suspension the paw volume was reduced by 56.61% at after 4 hour, whereas in case of the same extract at 150 mg/kg body weight per day shows 61.12% inhibition at same time. Hence, methanolic extract exhibited considerable anti-inflammatory activity at the dose of 100mg/kg body weight, produced a significant inhibition of inflammation compared with Indomethacin (100 mg/kg) as standard reference and normal saline as control.

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