Phytochemical and Antimicrobial studies of stembark extracts from Uapaca pilosa (Hutch.)

Author : George I. Ndukwe, Muhammed S. Sallau and Ayodele J. Atibioke

Objectives: To determine the antimicrobial activity and to also detect the phytoconstituents that are present in the various fractions of the crude extract of Uapaca pilosa. Methods: The antimicrobial and medicinal properties of Uapaca pilosa stembark extracts was examined through phytochemical screening and bioassay on some selected microorganisms: E. coli, S. typhill, S. aureus, B. sbstilis, S. dysenteriae, C. albicans and C. krusei. Result: The preliminary phytochemical screening of the plant extracts were assessed using standard methods. Test for the following active components: alkaloid, anthraquinones, carbohydrate, flavonoids, saponins, glycosides and tanins. All were present. The n-hexane extract show more activity against most of the selected microorganisms than other fractions of the plant extracts measuring clear zones of inhibition of between 10mm and 18mm. but none of the extracts show activity against C. albican and C. krusei. This shows that the bioactive components present in Uapaca proves potency in the treatment of some bacterial infections. Conclusion: the results could justify the use of the plant Uapaca pilosa in traditional herbal medicine for the treatment of bacterial infections.

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