Phytochemical and Pharmacological Screening of the fruits of Lagerstroemia speciosa (L.) pers.

Author : Sm Faysal Bellah, KM Rezwanul Islam, Md. Rezaul Karim, Md. Jahangir Hossain, Md. Ashrafudoulla and Mehedee Hasan

The present piece of work was framed to investigate the phytochemical screening along with pharmacological activities (analgesic, cytotoxicity and antibacterial activity) of the ethanolic fruit extract of the plant Lagerstroemia speciosa (L.) from family of Lythraceae. Phytochemical tests confirmed Steroids, Tannins and Saponins as its constituent compounds. Presence of these compounds further provoked to check for possible analgesic and cytotoxic activities of L. speciosa. The crude extract at the dose of 500 mg/kg body weight exhibited moderate analgesic action against acetic acid induced pain in Swiss albino mice, where percentage of protection was found 55.21% while the percentage of protection for standard drug diclofenac was 84.37% at a measure of 25 mg/kg body weight and the result was statistically significant (p<0.01). The extract also showed potent cytotoxic activity in brine shrimp where LC50 and LC90 was found at the dose of 60 g/ml and 100 g/ml respectively.

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