Prescribing pattern of anti-tubercular drugs in a tertiary care hospital

Author : S. M. Biradar, Prudvi C, Gaurav Joshi, Janak V. Patel, N. V. Kalyane, Prabhath A J

The observational and prospective study was undertaken to assess the prescribing pattern of anti-TB drugs. Among the selected 81 patients 63 (77.78%) were males & 18 (22.22) were females. The maximum numbers of patients were in the age group of 26 to 45 yrs. The patients were screened for sputum sensitivity and classified into normal TB and MDR-TB patients. The often risk factor involved in TB was tobacco chewing (54) followed by smoking (37). The TB was Co-morbid with RVD (24) and anaemia (14). The drug regimen followed in the study was traditional anti-TB drugs (73) and DOTs therapy (08). The patients treated with DOTs therapy was successful and shown culture sensitivity test negative and patientís compliance was very high with DOTs therapy. Some of ADRs were seen with the DOTs therapy, such as skin rashes, nausea, vomiting and brick red urine. As the anti-TB drugs more interacting and often ADRs exhibiting agents, a proper supervision of drug administration is needed under the guidance of clinical pharmacist with other health care professionals in order to reduce the incidence of ADRs, proper management of drug-drug interactions, avoidance of drug resistance and improve the patient compliance.

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