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Study of fungal infection in Iraqi patients suffering from chronic cough and antifungal sensitivity test in vitro for the fungi isolated from these patients

Author : Heba F. Hassan, Nada S. Hassain, Zainab A. Aldhaher, Rasha M. Shaker, Jamal A. Tawfeeq and Ghada Ibraheem

Aim and Objective: This study was undertaken to determine isolation of Aspergillus species and candida species from sputum samples in patients suffering from chronic cough and used antifungal sensitivity test in vitro for the fungi isolated from these patients and for the purpose of access to the remarkable progress in the field of fungal treatment. Methods: Sputum samples were collected from 62 patients and controls for isolation of Aspergillus species and yeast and in vitro antifungal sensitivity test Results: A total of forty sputum samples from the patient with chronic cough were isolated and identified, the result of fungal growth of the sputum samples, the isolates are Aspergillus fumigatus 14 (35%) and Candida. albicans 12(30%), it was revealed that Amphotericin B 24(60%) was more sensitive and effective antifungal drugs while Ketoconazole 27(67.5%) was more resistant and poor antifungal drug. Conclusion: The present study revealed that Aspergillus fumigatus was he present study revealed that Aspergillus fumigatus was more species isolates from sputum samples from the patients with chronic cough and Amphotericin B was more sensitive and effective antifungal drugs for the fungi isolated from sputum samples.


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