Article

Study potentialities aphrodisiac of the peels of Buchholzia coriacea Engl.(caparidaceae) at the male mice

Author : R. Ondele; A. W. Etou Ossibi; M. B. Peneme; R.D.G Elion Itou; C. J. Moranbandza; G. F. Nsonde Ntandou; A. Binimbi Massengo; A. A. Abena

This work is about the study of the aphrodisiac potentialities of the peels of Buchholzia coriacea (Capparidaceae) at the male rat. The acute toxicity has been valued according to the OECD, while managing by oral way the aqueous extract of the plant to the respective doses of 2000 and 5000mg/kg. The mice witnesses had received water distilled to 0,5 ml/100g. The sexual parameters (sexual mounts, erections number; ejaculations number and the time of latency) have been valued after administration by oral way to the male rats the aqueous excerpt of B. coriacea (100,250 et500mg/kg per day). The fashion of action of the extract of the plants has been clarified at the rat in presence of the LNAME, the atropine and the haloperidol. The animals receive each 10 mg/kg of consistent antagonist of 100 mg/kg of the aqueous extract of the plant one hour before the mating. He/it is evident from this survey that, the extract of the plant doesn't provoke the death of the mice to the doses of 2000 and 5000 mg/kg. The LD50 is estimated to superior doses to 5000mg/kg. The aqueous of the peels of Buchholzia coriacea encourages the meaningful increase (P <0,05; P <0,01 ;PS <0,001) of the sexual parameters at the male rat to the doses of 100 ;250 and 500 mg/kg. The aqueous excerpt of the peels would act as the dopamine and the acetylcholine. The other studies aimed, will complete some information on the aphrodisiac effect of the plants.


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